In Episode 130 of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, is joined by Hunter Rondeau, PharmD, BCIDP, AAHIVP, antimicrobial stewardship coordinator at SSM Health, to explore the growing role of single-dose aminoglycosides for urinary tract infections with limited oral treatment options.
Hunter shares how this strategy gained traction through emergency department culture-callback programs and antimicrobial stewardship efforts, highlighting real-world scenarios where a single IV dose can prevent unnecessary admissions, PICC placement, and prolonged antibiotic exposure. The discussion dives into the evolving resistance landscape, the rise of ESBL and CRE organisms, and the clinical decision-making needed to identify the right patients for this approach.
Jimmy and Hunter also review key evidence, including systematic reviews, IDSA guidance, and emerging emergency medicine data that support the safety and effectiveness of single-dose aminoglycosides. From patient selection and workflow implementation to provider education and follow-up, this episode offers practical insights for pharmacists looking to expand their impact in the ED and beyond.
If you’re interested in antimicrobial stewardship, emergency medicine pharmacy, and innovative ways to manage resistant UTIs while keeping patients out of the hospital, this episode is packed with pearls you can apply in practice.
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The Pharm So Hard Podcast is a show focused primarily on emergency medicine and hospital pharmacy related topics. To empower healthcare providers with the knowledge and skills they need to provide evidence-based, safe care for critically ill patients.
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