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Welcome to Pharm So Hard Podcast Website

Episode 54. Pharm So Hard Spotlight & 2 Year Anniversary with Joshua Kiptoo, Dan Giddings, and Christian Kroll

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Episode 53. I Love These Jeans! Pharmacogenomics with Amanda Elchynski

Looking for our premium material ? Head over to the PACU at Pharmacy-Acutecareuniversity.com

Episode 52. Just A Diet Prop for Me: Post-Intubation Analgesia and Sedation

Introduction Rapid sequence intubation (RSI) is a process whereby an induction agent and a neuromuscular blocking agent are given in rapid succession to facilitate endotracheal intubationThe immediate post intubation period in the ED is a critical time for continued...

Episode 50. The Immune System Needs to Calm Down: Pharmacologic Management with Tocilizumab and Baricitinib

Tocilizumab and Baricitinib Mechanisms of Action COVID-19 Pathogenesis: Late COVID-19 In the late stage, pulmonary edema can fill the alveolar spaces with hyaline membrane formation, compatible with early-phase acute respiratory distress syndrome (ARDS). Joost...

Episode 49. Stay off the Weed! The Pharmacologic Management of Cannabinoid Hyperemesis Syndrome

Episode Summary: In this episode of Pharm So Hard, Jimmy Pruitt, PharmD, BCPS, BCCCP discuss the pharmacotherapy of cannabinoid hyperemesis syndrome. https://youtu.be/MKhBaMLCQXY

Why Are You So Salty! Intracranial Pressure Reduction with Morgan Jones

https://youtu.be/jiKIukL_GF0 Questions asked throughout the episode Can you describe pathophysiology of elevated ICP or cerebral edema? "I always teach trainees that as long as you understand the pathophysiology behind a problem and the mechanisms behind the drugs we...
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Episode 47. I Plead the Fifth! 5 vs 10 units of Insulin for Hyperkalemia

To view the handout for the Pharmacy Friday Pearl visit: https://www.pharmacy-pearls.com/home Introduction Insulin with dextrose is an effective method to lower potassium levels quickly in acute hyperkalemiaLiterature shows ranges of potassium reduction by 0.5-1.0 mEq...

Episode 46. Do Better! How to Become a Super Nurse in the ED with Brian Cox, RN

https://youtu.be/tu5io0COUzU Episode Summary In this episode of the Pharm So Hard Podcast, Jimmy Pruitt PharmD, BCPS, BCCCP discuss with Brian Cox, RN the various tasks and skills that we can improve on in the ED.Tweet Podcast Script Intro 0-3:17 EKG 3.21-8.24 IV...

Emergency Medicine Clinical Pharmacy Map

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Jimmy Pruitt

Episode 45. Staying Fabulous with Fabs: Pharmacologic Management of Snake Bites with Crofab and Anavip

Introduction Around 9,000 Americans are treated for snake bites and 5 die each year. Most are bitten by members of the Crotalinae subfamily (a.k.a. crotalids) of the pit viper family which includes copperheads, water moccasins, and rattlesnakes.Tweet Crotalid...

Episode 44. Keeping Up With COVID-19: Revisiting Remdesivir with Theora Canonica, Pharm D

Series Title: Keeping Up With COVID-19 Part 2:  Revisiting Remdesivir Situation (Jimmy).We are over a year into this pandemic and we have only one FDA approved medication for the treatment of COVID-19: Remdesivir.The purpose of this episode is to briefly review...
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Episode 43: Put It in Reverse Terry! Fixed-Dosed Kcentra for Vitamin K Antagonist Reversal

References Kcentra (prothrombin complex concentrate [Human]) [package insert]. Kankakee, IL: CSL Behring LLC; 2013.Tomaselli, Gordon F., et al. "2017 ACC expert consensus decision pathway on management of bleeding in patients on oral anticoagulants: a report of the...

Episode 42. Residency Here I Come! The Pharm So Hard Residency Panel

Residency Panel Sarah CummingsPharmD: Purdue PGY1: Thomas Jefferson University HospitalPGY2 EM 2020-21: UC DavisBritany ByrkitPharmD: WingatePGY1: Vidant Medical CenterPGY2 EM 2020-21: MUSC HealthTramauni E. BrockPharmD: Texas Southern University PGY1: MUSC Health...

Episode 41: Scratch the Gent! Antibiotics for Open Fractures with Rob O’Connell

Why this topic important?Accidental injury is the most common cause of death in the United States in individuals between the ages of 1 and 45Falls are the most common reasons for hospital admissions in this older age group and account for 87% of fractures.Open...

Episode 40: Leveling Up As a Clinical Staff Pharmacist by oscar Santalo and Jimmy Pruitt

Background For continued growth and development, hospital pharmacist would benefit from leadership trainingPharmacy schools provide some administrative trainingHospital pharmacist may one day want to become a clinical or operations managerWith an increase in residency...
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Episode 39: Welcome to the Block Shop! Regional Anesthesia with Drs. Shah, CUmmings, Oliva, and Moake

Show Notes 0:25 Introduction2:30 The importance of ultrasound-guided peripheral nerve blocks3:49 Overview of ultrasound-guided peripheral nerve blocks4:40 What are the training and credential required to perform ultrasound-guided peripheral nerve blocks7:58 What does...

The beef with Bicarb Part 3. The Use of Sodium Bicarbonate in Cardiac Arrest by Jimmy Pruitt

Show Timestamps 1:14 Review of previous episodes of the series2:40 Pharmacy Friday Pearls3:24 EMPoweRx Conference5:28 Cardiac Arrest Patho of Acidosis6:04 Why have we been using sodium bicarbonate7:08 Adverse Effects of sodium bicarbonate9:29 History of sodium...

Taking it Brain to Vein by PharmD_intheeD

Lyrics Brain to Vein  Hook All you gotta do is try to maintainCause we taking that thang ....... (straight from where) brain to veinAll you got to is make sure you treat the pain,Cause we taking that thang ....... (straight from where) brain to veinAll you got to...

Episode 35: Why Meetings Fail with Oscar Santalo

Importance of Meetings •Establishes alignment: allows for discussion of complex issues and for the team to get on the same page. Helps leaders make better decisions when gaining insight from the team •Builds stronger relationships: free-flowing ideas and personal...
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Episode 34: The Beef with Bicarb Part 2: The Use of Sodium Bicarbonate for Diabetic Ketoacidosis

Pathophysiology of acidosis in DKA The unfavorable combination of insulin resistance and counter-regulatory hormones leads to the release of free fatty acids (FFA) from adipose tissue via lipolysis and decreased lipogenesis, which ultimately results in ketogenesis and...

Episode 32: Lean Thinking & Time Management in Pharmacy With Oscar Santalo

In this episode of Pharm So Hard, Oscar Santalo PharmD, MBA, MHA, BCPS with his learners Deanna Cordero Da Silva and Brandon Del Carpio PharmD 2021 candidates from the University of Florida School Of Pharmacy discuss Lean Thinking & Time Management.
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EPISODE 31: The Beef with Bicarb! The Use of Sodium Bicarbonate in Hyperkalemia with Jimmy Pruitt

Introduction Sodium bicarbonate was previously recommended for hyperkalemia treatment and was once considered a first-line agent for the transcellular shift.Studies evaluating the beneficial effects of sodium bicarbonate used an isotonic infusion commonly  ~ 150...
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Episode 29: I wasn’t going to get the COVID Vaccine until I answered these questions by Jimmy Pruitt

https://twitter.com/pharmso_hard/status/1338249445591355394 Why did I make this episode? FamilyFriendsCo-Workers Why I wasn’t going to get the COVID Vaccine Skeptical ofThe speed at which the vaccine was producedUnfamiliarity with the mRNA Technology usedEfficacy in...

Episode 27: Survey of Health-System Pharmacy Administration & Leadership Residencies

Definitions What is an HSPA Residency The Health-System Pharmacy Administration and Leadership (HSPA-L) Residency is a 24-month post- Doctor of Pharmacy training program. The PGY1 and PGY2 years are designed to flow seamlessly together, with no need to re-apply or...

Episode 26: The B52 is Trash! Going from the B52 to the 55 Blitz with Dan McCollum.

PMID: 9217519 PMID: 30206503 Pubmed ID: 10499950 Jimmy's Acute Agitation Guide Disclaimer This site is not meant to replace the judgement of healthcare professionals, and the information presented on this site does not represent the views or practices of the...

Episode 25: Pantoprazole Continuous infusion vs Intermittent Bolus Formulary Nugget by Oscar Santalo

Situation SituationPantoprazole 80 mg in NS 100 mL drip is being used for GI Bleeds due to ulcers Problem:Evidence not being clear on optimal dosing strategy Opportunity to:Standardize dosing strategies for upper and lower GI bleedsFollow best practice strategies...

Episode 21. We Belong Together – How to Interview like a boss with Oscar Santalo and Jonathan Richardson

Objectives Recognize the process of recruitmentUnderstand the methods of candidate selectionReview the components of staff retention Components of Recruitment Position descriptionSourcesPre-interview information Position Description Examples Position title, control...

Episode 20: RSI From the Sky: Caring for Intubated Patients as a Flight Nurse with Everett Moss II, BSN, RN, NRP

Background Out-of-hospital tracheal intubation is an accepted practice that has increased in frequency due to advancements in aeromedical technology and transport. A flight nurse, sometimes referred to as a transport nurse, is an RN who is specially trained to provide...

Episode 19: Early ED Discharge in Patients with low-risk VTE with DOACs with Jimmy Pruitt and Oscar Santalo

Background In 2003 – 2014 inpatient hospital costs ranged from $3,018 to $5,040 per admission for a primary DVT diagnosisAverage DVT LOS can range from 4.9 – 7 daysRecurrent VTE that requires readmission could be up to 48% more costly than the initial eventProtocols...

Episode 18: The Management of Snake Bites with Craig Cocchio, PharmD, DABAT

Background More than 3,000 species of snakes are identified worldwide, with nearly 800 species considered venomous.All venomous species are classified taxonomically into one of 4 general groups.These include the families Viperidae, Elapidae, and Colubridae, as well as...

Episode 17: Do You Even Lift – Looking At The Metrics Used For External Benchmarking with Oscar Santalo and Joanna Longueira

Definitions Benchmarking - Finding and implementing the best practices.  Health-system administrators are turning to benchmarking vendors for help in improving operational performanceEfficiency - Avoiding waste or maximizing possible outputs from a set of...

Episode 16: How Much Do You Bench? An Overview on External Benchmarking with Oscar Santalo and Joanna Longueira

Definitions Benchmarking - Finding and implementing the best practices.  Health-system administrators are turning to benchmark vendors for help in improving operational performanceEfficiency - Avoiding waste or maximizing possible outputs from a set of resource...

Episode 15: Keeping Ahead of Coronavirus. Helpful Information During the COVID-19 Pandemic With Alaina Dekerlegand, PharmD, BCIDP

Stroll to the bottom for resources and protocols What is COVID-19 COVID-19 is a new strain of coronavirus first identified in December 2019 in Wuhan, China The disease was initially named Coronavirus disease 2019 (COVID-19). The virus has since been renamed Severe...

Episode 14: High-Dose Nitroglycerin for Sympathetic Crashing Pulmonary Edema (SCAPE) with Rachel Wein, PharmD, BCPS

Download Pharmacy Friday Pearl Handout High-Dose-Nitroglycerin-for-SCAPE-Handout.-pharmacy-friday-Pearls-2.0-Download Introduction Acute heart failure (AHF) is a common underlying cause for dyspnea in patients presenting to EDs around the globe.1-2  SCAPE is a...

Episode 13: Assessing Pharmacy Candidates for Pharmacy Residency Programs with Dan Hu

Questions for Dan Hu Can you descript how you got interested in evaluating pharmacy students for residency? What are some of the current challenges of evaluating students in the current model? Can you summarize your publication “ A Screening Tool to Identify Qualified...

Episode 12. Mergers and Acquisitions with Oscar Santalo PharmD, MBA, MHA, BCPS

Definition Merger & Acquisition - defined as the consolidation of companies.Differentiating the two terms, Mergers is the combination of two companies to form one, while Acquisitions is one company taken over by the other Background Throughout the 1990s, mergers...
Ruben Santiago, Pharm.D., BCPS, BCCCP, Emergency Medicine Clinical Pharmacist

Episode 11: The Role of an ED Pharmacist as Part of the Trauma Team with Ruben Santiago, Pharm.D., BCPS, BCCCP

In this episode of the Pharm So Hard Podcast, Jimmy Pruitt PharmD, BCPS discusses with Ruben Santiago, Pharm.D., BCPS, BCCCP the role of an ED Pharmacist as part of a trauma team.

Episode 10. Formulary Management with Oscar Santalo

Definitions Formulary medication - A determination that the medication is “appropriate for routine use” in select patient populationsPer 2008 ASHP Guidelines on the Pharmacy and Therapeutics Committee and the Formulary SystemPharmacy and Therapeutics (P & T)...

Episode 9: The Treatment of Symptomatic Hyponatremia with Hypertonic Saline with Jimmy Pruitt

In this episode on The Pharm So Hard Podcast, Jimmy Pruitt, PharmD, BCPS discusses the treatment of symptomatic hyponatremia using hypertonic saline.

Episode 8: The Transition from Pharmacy School to Residency with the Pharmacy Twins Ashley & Brooke Barlow

In this episode on The Pharm So Hard Podcast, Jimmy Pruitt, PharmD, BCPS and Ashley & Brooke Barlow PharmD, BCPS discuss growing up as twins, making quality infographics, ASHP Midyear, and the pursuit of residency training.

Episode 6: Opioid Stewardship Part 2 with Oscar Santalo and Olga Ivanova

Oscar Santalo PharmD, MBA, MHA, BCPS Definition Opioid Sparing – providing multi – modal medications that limit the use and supply of opioidsOpioids - a class of drugs that act in the nervous system to produce feelings of pleasure and pain relief. Opioid...

Episode 5: Opioid StewardshipPart 1 with Oscar Santalo and Olga Ivanova

Oscar Santalo PharmD, MBA, MHA, BCPS Definitions Opioid Sparing – providing multi – modal medications that limit the use and supply of opioidsOpioids - a class of drugs that act in the nervous system to produce feelings of pleasure and pain relief. Opioid...

5-Minute Pharmacy Pearl: Single Syringe of Diluted Adenosine for Termination of SVT

Dosing Supraventricular tachycardia adenosine 6 milligrams (mg) may be given over 1 to 2 seconds followed by a 20 milliliter (mL) rapid saline flush. If there is no response in 1 to 2 minutes, a 12 mg IV bolus dose may be repeated twice followed by saline...

Episode 4: Drugs Trends in Pharmacy with Oscar Santalo and Darla Quevedo

Oscar Santalo, PharmD, MBA, MHA, BCPS Pharmacy Operations and Compliance Coordinator Episode 4 Description: In this episode of Pharm So Hard, Oscar Santalo PharmD, MBA, MHA, BCPS with his learner Darla Quevedo PharmD 2021 candidate from the University of Florida...

Episode 3: Transitioning from Resident to EM Pharmacy Practitioner with Kyle Hultz

Kyle Hultz, Pharm.DEmergency Medicine Clinical PharmacistTwitter: PharmDAware In this episode of Pharm So Hard, Jimmy Pruitt, Pharm.D and Kyle Hultz, Pharm.D discuss the excitement and the challenges of transitioning from residency to the role of an emergency medicine...

Episode 2: Factor Xa Inhibitor Reversal Using Andexxa with Gary Peksa

Gary Peksa, PharmD, BCPSEmergency Medicine Pharmacist Coagulation factor Xa [recombinant], inactivated-zhzo ( Andexxa ) Mechanism of Action Andexanet alfa binds and sequesters the FXa inhibitors rivaroxaban and apixaban. In addition, andexanet alfa inhibits the...

Episode 1: Factor Xa Inhibitor Reversal Using PCC with Brian Gilbert

Brian Gilbert, PharmD, BCPS, BCCCPEmergency Medicine Pharmacist http://feeds.soundcloud.com/stream/679237017-pharmsohard-episode-1-factor-xa-inhibitor-reversal-using-pcc-with-brian-gilbert.mp3 Pharmacology AgentApixabanRivaroxabanWarfarinDabigatranMechanism of...
Episode 34: The Beef with Bicarb Part 2: The Use of Sodium Bicarbonate for Diabetic Ketoacidosis

Episode 34: The Beef with Bicarb Part 2: The Use of Sodium Bicarbonate for Diabetic Ketoacidosis

Pathophysiology of acidosis in DKA The unfavorable combination of insulin resistance and counter-regulatory hormones leads to the release of free fatty acids (FFA) from adipose tissue via lipolysis and decreased lipogenesis, which ultimately results in ketogenesis and...

Episode 29: I wasn’t going to get the COVID Vaccine until I answered these questions by Jimmy Pruitt

Episode 29: I wasn’t going to get the COVID Vaccine until I answered these questions by Jimmy Pruitt

https://twitter.com/pharmso_hard/status/1338249445591355394 Why did I make this episode? FamilyFriendsCo-Workers Why I wasn’t going to get the COVID Vaccine Skeptical ofThe speed at which the vaccine was producedUnfamiliarity with the mRNA Technology usedEfficacy in...

Episode 19: Early ED Discharge in Patients with low-risk VTE with DOACs with Jimmy Pruitt and Oscar Santalo

Episode 19: Early ED Discharge in Patients with low-risk VTE with DOACs with Jimmy Pruitt and Oscar Santalo

Background In 2003 – 2014 inpatient hospital costs ranged from $3,018 to $5,040 per admission for a primary DVT diagnosisAverage DVT LOS can range from 4.9 – 7 daysRecurrent VTE that requires readmission could be up to 48% more costly than the initial eventProtocols...

Episode 15: Keeping Ahead of Coronavirus. Helpful Information During the COVID-19 Pandemic With Alaina Dekerlegand, PharmD, BCIDP

Episode 15: Keeping Ahead of Coronavirus. Helpful Information During the COVID-19 Pandemic With Alaina Dekerlegand, PharmD, BCIDP

Stroll to the bottom for resources and protocols What is COVID-19 COVID-19 is a new strain of coronavirus first identified in December 2019 in Wuhan, China The disease was initially named Coronavirus disease 2019 (COVID-19). The virus has since been renamed Severe...

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